Question: Which Parent Carries The Gene For Cystic Fibrosis?

What is the oldest person with cystic fibrosis?

The oldest person diagnosed with CF for the first time in the U.S.

was 82, in Ireland was 76, and in the United Kingdom was 79..

What gender is cystic fibrosis most common in?

Cystic fibrosis affects both males and females; approximately 30,000 people in the United States have been diagnosed with the condition.

Who carries the cystic fibrosis gene?

To have cystic fibrosis, a child must inherit one copy of the cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation from each parent. People who have only one copy of a CFTR gene mutation do not have CF. They are called “CF carriers.”

Do carriers of cystic fibrosis have any symptoms?

Although cystic fibrosis carriers do not have CF and are generally asymptomatic, there is emerging research which is finding that some carriers may have very mild symptoms associated with the genetic mutation. These symptoms may be a very pale shadow of the more severe symptoms someone with CF has.

Can you get cystic fibrosis without family history?

Yes. In fact, most couples who have a child with CF have no family history of cystic fibrosis and are surprised to learn that they carry a mutation in the CFTR gene, which causes the condition. Genes are the basic hereditary units determining an individual’s traits, such as hair and eye color.

How can a child inherit cystic fibrosis if neither parent has the disease?

Inherited, or genetic, diseases like cystic fibrosis (CF) are passed from parents to their children. This occurs even when neither parent has the disease. For a child to inherit CF, both parents must have an altered gene that causes CF; that is, both parents must be carriers of an altered CF gene.

What if only one parent is a CF carrier?

If only one parent is a carrier of a defective CF gene, the child will not have CF. But there is a 50% (1-in-2) chance that the child will be a CF carrier. If both parents are carriers, there is a 25% (1-in-4) chance that the child will have CF, and a 50% chance that the child will be a carrier.

Can cystic fibrosis be inherited from one parent?

Cystic fibrosis is inherited in an autosomal recessive manner. Our genes come in pairs, with one copy inherited from each parent. Some genes have mutations in them, and do not function properly. A person with one non-functional copy of the gene is a carrier.

Can you have a mild form of cystic fibrosis?

Atypical CF is a milder form of the CF disorder, which is associated with mutations of the cystic fibrosis transmembrane receptor gene. Instead of having classic symptoms, individuals with atypical CF might only have mild dysfunction in 1 organ system and might or might not have elevated sweat chloride levels.